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"Reishi a popular medicinal mushroom, has been used in China for longevity and health promotion since ancient times. Investigations into the anti cancer activity of reishi have been performed in both in vitro and in vivo studies, supporting its application for cancer treatment and prevention. The proposed anti cancer activity of reishi has prompted its usage by cancer patients. It remains debatable as to whether reishi is a food supplement for health maintenance or actually a therapeutic "drug" for medical proposes.
Thus far there has been no report of magic mushrooms for sale human trials using reishi as a direct anti cancer agent, despite some evidence showing the usage of reish as a potential supplement to cancer patients. Cellular immune responses and mitogenic reactivity of cancer patients have been enhanced by reshi, as reported in two randomized and one nonrandomized trials, and the quality of life of 65% of lung cancer patients improved in one study. The direct cytotoxic and anti-angiogenesis mechanisms of reishi have been established by in vitro studies; however, clinical studies should not be neglected to define the applicable dosage in vivo. At present, reishi is a health food supplement to support cancer patients, yet the evidence supporting the potential of direct in vivo anti cancer effects should not be underestimated."